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- $Unique_ID{BRK03585}
- $Pretitle{}
- $Title{Chalazion}
- $Subject{Chalazion Meibomian Cyst Tarsal Cyst Hordeolum Internal Hordeolum
- External Sty Blepharitis}
- $Volume{}
- $Log{}
-
- Copyright (C) 1989 National Organization for Rare Disorders, Inc.
-
- 702:
- Chalazion
-
- ** IMPORTANT **
- It is possible that the main title of the article (Chalazion) is not the
- name you expected. Please check the SYNONYM listing to find the alternate
- names and disorder subdivisions covered by this article.
-
- Synonyms
-
- Meibomian Cyst
- Tarsal Cyst
-
- Information on the following diseases can be found in the Related
- Disorders section of this report:
-
- Hordeolum, Internal
- Hordeolum, External, (Sty)
- Blepharitis
- Tarsitis
- General Discussion
-
- ** REMINDER **
- The information contained in the Rare Disease Database is provided for
- educational purposes only. It should not be used for diagnostic or treatment
- purposes. If you wish to obtain more information about this disorder, please
- contact your personal physician and/or the agencies listed in the "Resources"
- section of this report.
-
- Chalazion is a chronic tumor-like mass (granuloma) in the connective
- tissue of the eyelid (tarsus) caused by an inflammation of the meibomian
- gland.
-
- Symptoms
-
- Chalazion is a chronic inflammation of the meibomian gland and is
- characterized by an irritation and swelling of the eyelid. There may be a
- small, round, moveable swelling of the meibomian gland. The inflammation is
- usually painless unless it enlarges and causes an inflamation of the eyelids'
- membrane (conjunctiva).
-
- Causes
-
- The exact cause of Chalazion is not known. It is thought to be caused by a
- blockage of the duct of the oil-producing meibomian gland.
-
-
- Affected Population
-
- Chalazion affects males and females in equal numbers.
-
- Related Disorders
-
- Symptoms of the following disorders can be similar to those of Chalazion.
- Comparisons may be useful for a differential diagnosis:
-
- A Sty (External Hardeolum) is an acute, localized infection of one of the
- glands of the eyelid. It is a common condition characterized by pain,
- redness, and a small and round localized area of inflammation. A small
- yellow spot of pus will appear at the top of the swollen area. This will
- eventually rupture, draining the infection and relieving the pain. A sty is
- treated with hot compresses to promote drainage and antibiotic ointments.
-
- Internal Hardeolum is a more severe and deeper infection of the meibomian
- gland. There is more localized pain, redness and swelling. On the inside of
- the eyelid a swelling occurs that may become abscessed. Rupture of the
- inflamed area is rare and repeat episodes are common. This disorder is
- treated with hot compresses and antibiotics. The drug Sulfacetemide may be
- used to prevent the infection from spreading to other areas of the body.
-
- Blepharitis is an inflammation of the eyelids. Nonulcerative (squamous or
- seborrheic) blepharitis is characterized by itching, redness, swelling, loss
- of eye lashes, a discharge and irritation of the conjunctiva, excessive
- tearing, and sensitivity to light. It may be caused by an allergic reaction
- or an excess secretion of sebum of the face and scalp. With ulcerative
- blepharitis, a bacterial infection (usually staphylococcal) of the eyelids
- occurs causing pustules, crusts and ulcers of the eyelids. Treatment
- consists of topical antibiotics and warm compresses applied to the affected
- eye. Sulfacetemide-corticosteroid drops can be helpful in controlling
- further infections.
-
- Tarsitis is an inflammation of the eyelids that may be caused by
- syphilis, tuberculosis or trachoma (an infectious disease of the conjunctiva
- and cornea). It is characterized by redness, swelling, tenderness, and pain
- in the eyelid. There may also be pus, crusts of the eyelash follicles and
- soft skin tumors (gummata) which may cause a thickening of the connective
- tissues of the eyelid (tarsus). This type of tumor may indicate a late stage
- of syphilis. Parenteral Penicillin G has proven effective in the treatment
- of nonallergic patients with Syphilis.
-
- Therapies: Standard
-
- Chalazions will often subside after a few months. The application of hot
- compresses, and topical antibiotic ointments such as bacitracin and
- erythromycin, may be effective. If necessary, surgical removal can be done
- under local anesthesia usually in the Ophthalmologist's office. Wearing an
- eye patch may be required for about a day.
-
- Therapies: Investigational
-
- At the present time, a study is being conducted on the effectiveness of CO2
- (carbon dioxide) laser therapy for the removal of Chalazion. Studies are also
- being conducted using intralesional corticosteroid injections with or without
- surgical removal of the chalazion. More research must be conducted to
- determine long-term safety and effectiveness of these treatments.
-
- This disease entry is based upon medical information available through
- December 1989. Since NORD's resources are limited, it is not possible to
- keep every entry in the Rare Disease Database completely current and
- accurate. Please check with the agencies listed in the Resources section for
- the most current information about this disorder.
-
- Resources
-
- For more information on Chalazion, please contact:
-
- National Organization for Rare Disorders (NORD)
- P.O. Box 8923
- New Fairfield, CT 06812-1783
- (203) 746-6518
-
- Eye Research Institute of Retina Foundation
- 20 Staniford St.
- Boston, MA 02114
- (617) 742-3140
-
-
- NIH/National Eye Institute
- 9000 Rockville Pike
- Bethesda, MD 20892
- (301) 496-5248
-
- References
-
- THE MERCK MANUAL, Volume 2, 14th Ed.: Robert Berkow, M.D. ed-in-chief;
- Merck, Sharp & Dohme Laboratories., 1982. Pp. 177.
-
- LASER CHALAZION REMOVAL. E.L. Korn; OPTHALMIC SURG, (June 1988; issue 19
- (6)). Pp. 428-431.
-
- COMBINED EXCISION AND DRAINAGE WITH INTRALESIONAL CORTICOSTEROID
- INJECTION IN THE TREATMENT OF CHRONIC CHALAZIA. G.A. Epstein et al.; ARCH
- OPTHALMOL, (April 1988; issue 106 (4)). Pp. 514-516.
-
- ADRENOCORTICOSTEROID INJECTION VS. CONSERVATIVE THERAPY IN THE TREATMENT
- OF CHALAZIA. G.W. Garrett et al.; ANN OPTHALMOL, (May 1988; issue 20 (5)).
- Pp. 196.
-
- EXTRATARSAL CHALAZIA. R.S. Gonnering; BR J OPTHALMOL, (March 1988; issue
- 72 (3)). Pp. 202-205.
-
-